The Institute for Basic Science (IBS) of South Korea invented Nano-MIND, which uses magnetic fields to wirelessly control brain regions. This novel technology allows for the modulation of animals’ motivation, social behaviors, and emotions.
This groundbreaking neuroscience method was published in Nature Nanotechnology. Because magnetic fields may penetrate biological tissues, they have been employed safely in medical imaging for years. Scientists have struggled to precisely regulate brain circuits with magnetic fields—until now.
Nano-MIND stimulates brain circuits with magnetic fields and nanoparticles. This achievement relies on nano-magnetoreceptor implantation in certain neurons and brain circuits. These receptors can be engaged by rotating magnetic fields at specific intervals to control brain activity.
In tests, nano-MIND activated inhibitory GABA receptors in the medial preoptic area (MPOA), a part of the brain that controls how mothers behave. Activating these neurones in non-maternal female mice improved their nurturing behaviours, such as bringing pups to their nest, mirroring maternal mice.
The technique also targeted lateral hypothalamic incentive circuitry to regulate food. In mice, activating these inhibitory neurones increased hunger and eating by 100%. In contrast, stimulating excitatory neurons reduced hunger and intake by over 50%.
Nano-MIND can selectively activate brain circuits and alter higher brain functions, expanding neuroscience research and treatment options. Controlling brain activity could lead to novel neurological and psychological treatments with this technology.
Nano-MIND’s animal model success suggests viable human applicability. This technology may transform how we study and treat complicated brain functions and illnesses as research continues.
